Carolinas Collaborative

This multi-site CTSA Translational Research Pilot Program is offering the opportunity for investigators to use electronic health records from multiple health systems in clinical research.

Four CTSAs (Duke University, the Medical University of South Carolina, the University of North Carolina at Chapel Hill‐RTI partnership, and Wake Forest University) have partnered with Health Sciences South Carolina (HSSC) to create this pilot program designed to encourage and facilitate novel clinical and translational research that applies or accelerates discovery into testing in clinical or population settings.

The Carolinas Collaborative is a data resource that harmonizes the electronic health record data across local CTSA institutions to expedite clinical research and quality improvement activities.

The proposed pilot work should collect preliminary data to lead to a competitive proposal submitted to an external funding agency (NIH, AHRQ, PCORI, foundation, etc.) within one year from onset of funding.

Projects must demonstrate high translational potential with a clear path to subsequent grant support for a cohort study or clinical trial. Population health improvement projects should demonstrate significant stakeholder involvement to move it into broader practice patterns, clinical guidelines, and other applications.

Projects must use the component EHR data warehouses from at least two of the four CTSAs. The individual CTSAs, in collaboration with Health Sciences South Carolina (HSSC), will assist funded awardees in data harmonization activities across the multiple sites using tools including i2b2 and SHRINE.

View and download the RFA

2018 Applications are now open. 

Key Application Dates

  • Informational Webinar: June 29, 2018 | 10:00–11:00 a.m. 
  • Application Submission Deadline: August 15, 2018 at 5:00 p.m.
  • Selection of Awardees: by September 30, 2018
  • Funding period: 12 months beginning no more than 60 days after notification of the award and ending no later than November 30, 2019.

View and download the RFA here.(link is external)

Register for the informational webinar here.

​The slides will be made available for anyone who cannot join this optional educational event.

Apply online

(This program uses the UNC online submission system).