The Duke Clinical & Translational Science Institute supports several biobanking efforts across campus, providing expertise to support the development of new biobanks, opportunities for enhancement of existing Duke biobanks, and connecting researchers to sources for external biobanking.
CTSI provides consultation in developing biobank infrastructure and improving the financial and operational viability of academic-based biobanks. Project leader support is also available to support proposals for translational research projects that include biospecimens.
The DTRI manages biobanking for the Duke MURDOCK Study, which has collected more than 400,000 blood and urine biospecimens from participants in this longitudinal health study. MURDOCK Study samples are stored by LabCorp in a biorespository just minutes from the MURDOCK Study office at the North Carolina Research Campus in downtown Kannapolis, NC.
The DTRI's biobanking assets also include the Biofluids Shared Resource (formerly the DNA Bank), which houses ~500,000 biospecimens. The Biofluids Shared Resource offers sample prep and extraction, DNA and RNA testing, and long-term storage for investigator biospecimen collections.
In addition, the Duke Biobank is based in CTSI and supported by the Duke School of Medicine. The Duke Biobank is a virtual organization that bridges existing biobanks across campus by harmonizing infrastructure, terminology and informed consents for biospecimens. It leverages the strengths of existing biobank facilities and also promotes best practices in biobanking.
The Duke Biobank manages a searchable Index of Biospecimens of Duke collections and is implementing LabVantage®, a robust biobanking information management system that will further standardize biobanking operations at Duke. LabVantage includes physical location of specimens as well as relevant clinical annotation.
Senior Director, Biobanking and Translational Research Core
Associate Dean, Regulatory Oversight and Research Initiatives