CTSI Duke Kannapolis Publications

The Duke Clinical and Translational Science Institute (CTSI) is part of the Clinical and Translational Science Award (CTSA) program funded by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) (Grant Number UL1 TR002553, KL2 TR002554, or TL1 TR002555). The content of this website is solely the responsibility of CTSI and does not necessarily represent the official views of the NIH.

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  1. Zhou Y, Turner EL, Simmons RA, Li F. Constrained randomization and statistical inference for multi-arm parallel cluster randomized controlled trials. Stat Med. 2022;41(10):1862-1883. doi10.1002/sim.9333
  2. Williamson TL, Adil SM, Shalita C, Charalambous LT, Mitchell T, Yang Z, Parente BA, Lee HJ, Ubel PA, Lemmon ME, Galanos AN, Lad SP, Komisarow JM. Palliative Care Consultations in Patients with Severe Traumatic Brain Injury: Who Receives Palliative Care Consultations and What Does that Mean for Utilization? Neurocrit Care. 2022. doi10.1007/s12028-021-01366-2
  3. Whitfield N, Gregory P, Liu B, Spratt S, Smith BH. Impact of pharmacist outreach on glucagon prescribing. J Am Pharm Assoc (2003). 2022. doi10.1016/j.japh.2022.01.017
  4. White MJ, Kay MC, Truong T, Green CL, Yin HS, Flower KB, Rothman RL, Sanders LM, Delamater AM, Duke NN, Perrin EM. Racial and Ethnic Differences in Maternal Social Support and Relationship to Mother-Infant Health Behaviors. Acad Pediatr. 2022. doi10.1016/j.acap.2022.02.008
  5. Wei X, Xiang Y, Peters DT, Marius C, Sun T, Shan R, Ou J, Lin X, Yue F, Li W, Southerland KW, Diao Y. HiCAR is a robust and sensitive method to analyze open-chromatin-associated genome organization. Mol Cell. 2022;82(6):1225-1238.e1226. doi10.1016/j.molcel.2022.01.023
  6. Vinson AJ, Dai R, Agarwal G, Anzalone AJ, Lee SB, French E, Olex AL, Madhira V, Mannon RB. Sex and organ-specific risk of major adverse renal or cardiac events in solid organ transplant recipients with COVID-19. Am J Transplant. 2022;22(1):245-259. doi10.1111/ajt.16865
  7. Tsai S, Truong T, Eaton JL. Fertility awareness and attitudes among resident physicians across different specialties. J Assist Reprod Genet. 2022;39(3):655-661. doi10.1007/s10815-022-02425-z
  8. Tsai S, Chung EH, Truong T, Farrell AS, Wu J, Ohamadike O, Eaton JL. Racial and ethnic disparities among donor oocyte banks in the United States. Fertil Steril. 2022;117(3):622-628. doi10.1016/j.fertnstert.2021.12.015
  9. Tejwani R, Lee HJ, Hughes TL, Hobbs KT, Aksenov LI, Scales CD, Routh JC. Predicting postoperative complications in pediatric surgery: A novel pediatric comorbidity index. J Pediatr Urol. 2022. doi10.1016/j.jpurol.2022.03.007
  10. Shelton RC, Dolor RJ, Tobin J, Baumann A, Rohweder C, Patel S, Baldwin LM. Dissemination and implementation science resources, training, and scientific activities provided through CTSA programs nationally: Opportunities to advance D&I research and training capacity. J Clin Transl Sci. 2022;6(1):10. doi10.1017/cts.2022.377
  11. Semmes EC, Li SH, Hurst JH, Yang Z, Niedzwiecki D, Fouda GG, Kurtzberg J, Walsh KM, Permar SR. Congenital Human Cytomegalovirus Infection Is Associated With Decreased Transplacental IgG Transfer Efficiency Due to Maternal Hypergammaglobulinemia. Clin Infect Dis. 2022;74(7):1131-1140. doi10.1093/cid/ciab627
  12. Schoen MS, Singh RH. Plasma metabolomic profile changes in females with phenylketonuria following a camp intervention. Am J Clin Nutr. 2022;115(3):811-821. doi10.1093/ajcn/nqab400
  13. Raja SM, Guptill JT, McConnell A, Al-Khalidi HR, Hartwig MG, Klapper JA. Perioperative Outcomes of Thymectomy in Myasthenia Gravis: A Thoracic Surgery Database Analysis. Ann Thorac Surg. 2022;113(3):904-910. doi10.1016/j.athoracsur.2021.06.071
  14. Raja SM, Guptill JT, Juel VC, Walter EB, Cohen-Wolkowiez M, Hill H, Sendra E, Hauser B, Jackson P, Tomic M, Espinoza Y, Swamy GK. First-in-Human Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of Single Doses of NTM-1633, a Novel Mixture of Monoclonal Antibodies against Botulinum Toxin E. Antimicrob Agents Chemother. 2022;66(4):e0173221. doi10.1128/aac.01732-21
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  16. Oyeyemi DM, Cooter M, Chung S, Whitson HE, Browndyke JN, Devinney MJ, Smith PJ, Garrigues GE, Moretti E, Moul JW, Cohen HJ, Mathew JP, Berger M. Relationship Between Depression/Anxiety and Cognitive Function Before and 6 Weeks After Major Non-Cardiac Surgery in Older Adults. J Geriatr Psychiatry Neurol. 2022;35(1):145-154. doi10.1177/0891988720978791
  17. Martin B, DeWitt PE, Russell S, Anand A, Bradwell KR, Bremer C, Gabriel D, Girvin AT, Hajagos JG, McMurry JA, Neumann AJ, Pfaff ER, Walden A, Wooldridge JT, Yoo YJ, Saltz J, Gersing KR, Chute CG, Haendel MA, Moffitt R, Bennett TD. Characteristics, Outcomes, and Severity Risk Factors Associated With SARS-CoV-2 Infection Among Children in the US National COVID Cohort Collaborative. JAMA Netw Open. 2022;5(2):e2143151. doi10.1001/jamanetworkopen.2021.43151
  18. Machen L, Davenport CA, Oakes M, Bosworth HB, Patel UD, Diamantidis C. Race, Income, and Medical Care Spending Patterns in High-Risk Primary Care Patients: Results From the STOP-DKD (Simultaneous Risk Factor Control Using Telehealth to Slow Progression of Diabetic Kidney Disease) Study. Kidney Med. 2022;4(1):9. doi10.1016/j.xkme.2021.08.016
  19. Limkakeng AT, Ye JJ, Staton C, Ng YY, Leong BSH, Shahidah N, Yazid M, Gordee A, Kuchibhatla M, Ong MEH. Impact of dispatcher-assisted cardiopulmonary resuscitation on performance of termination of resuscitation criteria. Resuscitation. 2022;170:160-166. doi10.1016/j.resuscitation.2021.11.034
  20. Levitt EB, Patch DA, Mabry S, Terrero A, Jaeger B, Haendel MA, Chute CG, Quade JH, Ponce B, Theiss S, Spitler CA, Johnson JP. Association Between COVID-19 and Mortality in Hip Fracture Surgery in the National COVID Cohort Collaborative (N3C): A Retrospective Cohort Study. J Am Acad Orthop Surg Glob Res Rev. 2022;6(1). doi10.5435/JAAOSGlobal-D-21-00282
  21. Knisely MR, Tanabe PJ, Walker JKL, Yang Q, Shah NR. Severe Persistent Pain and Inflammatory Biomarkers in Sickle Cell Disease: An Exploratory Study. Biol Res Nurs. 2022;24(1):24-30. doi10.1177/10998004211027220
  22. Kamp A, Huang W, Lassiter T, Shah S, Liu B, Kram B. Comparison of intermittent versus continuous infusion antihypertensives in acute ischemic stroke. Am J Emerg Med. 2022;52:220-224. doi10.1016/j.ajem.2021.11.037
  23. James AH, Federspiel JJ, Ahmadzia HK. Disparities in obstetric hemorrhage outcomes. Res Pract Thromb Haemost. 2022;6(1). doi10.1002/rth2.12656
  24. Ikram N, Frost A, LeMasters K, Hagaman A, Baranov V, Gallis J, Sikander S, Scherer E, Maselko J. Adverse childhood experiences and implications of perceived stress, anxiety and cortisol among women in Pakistan: a cross-sectional study. BMJ Open. 2022;12(4):11. doi10.1136/bmjopen-2021-052280
  25. Huang RJ, Riska KM, Gordee A, Peskoe SB, Francis HW, Witsell DL, Smith SL. The Association Between Hearing Loss and Surgical Complications in Older Adults. Ear Hear. 2022;43(3):961-971. doi10.1097/aud.0000000000001152
  26. Hosaka KRJ, Mmbaga BT, Shayo AM, Gallis JA, Turner EL, O'Donnell KE, Cunningham CK, Boshe J, Dow DE. A group-based mental health intervention for Tanzanian youth living with HIV: Secondary analysis of a pilot trial. Medicine (Baltimore). 2022;101(7):e28693. doi10.1097/md.0000000000028693
  27. Foster N, Shaffrey C, Buchholz A, Turner R, Yang LZ, Niedzwiecki D, Goode A. Image Quality and Dose Comparison of 3 Mobile Intraoperative Three-Dimensional Imaging Systems in Spine Surgery. World Neurosurg. 2022;160:e142-e151. doi10.1016/j.wneu.2021.12.103
  28. Eckhoff AM, Connor AA, Thacker JKM, Blazer DG, Moore HG, Scheri RP, Lagoo-Deenadayalan SA, Harpole DH, Seymour KA, Purves JT, Ravindra KV, Southerland KW, Rocke DJ, Gilner JB, Parker DC, Bain JR, Muehlbauer MJ, Ilkayeva OR, Corcoran DL, Modliszewski JL, Devos N, Foster MW, Moseley MA, Dressman HK, Chan C, Huebner JL, Chasse S, Stempora L, Aschenbrenner ME, Joshi MB, Hollister B, Henao R, Barfield RT, Ellison MA, Bailey S, Woody S, Huang ES, Kirk A, Hwang ES. A Multidimensional Bioinformatic Platform for the Study of Human Response to Surgery. Ann Surg. 2022. doi10.1097/sla.0000000000005429
  29. Dunn J, Shandhi MMH, Cho P, Roghanizad A, Singh K, Wang W, Enache O, Stern A, Sbahi R, Tatar B, Fiscus S, Khoo QX, Kuo Y, Lu X, Hsieh J, Kalodzitsa A, Bahmani A, Alavi A, Ray U, Snyder M, Ginsburg G, Pasquale D, Woods C, Shaw R. A Method for Intelligent Allocation of Diagnostic Testing by Leveraging Data from Commercial Wearable Devices: A Case Study on COVID-19. Res Sq. 2022. doi10.21203/
  30. Draelos RL, Ezekian JE, Zhuang F, Moya-Mendez ME, Zhang Z, Rosamilia MB, Manivannan PKR, Henao R, Landstrom AP. GENESIS: Gene-Specific Machine Learning Models for Variants of Uncertain Significance Found in Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome-Associated Genes. Circ Arrhythm Electrophysiol. 2022;15(4):e010326. doi10.1161/circep.121.010326
  31. Dow DE, O'Donnell KE, Mkumba L, Gallis JA, Turner EL, Boshe J, Shayo AM, Cunningham CK, Mmbaga BT. Sauti ya Vijana (SYV; The Voice of Youth): Longitudinal Outcomes of an Individually Randomized Group Treatment Pilot Trial for Young People Living with HIV in Tanzania. AIDS Behav. 2022;26(6):2015-2025. doi10.1007/s10461-021-03550-z
  32. Davidson BA, Puechl AM, Watson CH, Lim S, Gatta L, Monuszko K, Drury K, Ryan ES, Rice S, Truong T, Ma J, Power S, Jordan W, Kurtovic K, Havrilesky LJ. Promoting timely goals of care conversations between gynecologic cancer patients at high-risk of death and their providers. Gynecol Oncol. 2022;164(2):288-294. doi10.1016/j.ygyno.2021.12.009
  33. Darling AJ, Federspiel JJ, Wein LE, Swamy GK, Dotters-Katz SK. Morbidity of late-season influenza during pregnancy. Am J Obstet Gynecol MFM. 2022;4(1):100487. doi10.1016/j.ajogmf.2021.100487
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  35. Cho PJ, Yi J, Ho E, Shandhi MMH, Dinh Y, Patil A, Martin L, Singh G, Bent B, Ginsburg G, Smuck M, Woods C, Shaw R, Dunn J. Demographic Imbalances Resulting From the Bring-Your-Own-Device Study Design. JMIR Mhealth Uhealth. 2022;10(4):e29510. doi10.2196/29510
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  1. Wheeler SM, Myers SO, Swamy GK, Myers ER. Estimated Prevalence of Risk Factors for Preeclampsia Among Individuals Giving Birth in the US in 2019. JAMA Netw Open. 2022;5(1):e2142343. doi10.1001/jamanetworkopen.2021.42343
  2. Thaden JT, Tamma PD, Pan Q, Doi Y, Daneman N. Survey of infectious diseases providers reveals variability in duration of antibiotic therapy for the treatment of Gram-negative bloodstream infections. JAC Antimicrob Resist. 2022;4(1):dlac005. doi10.1093/jacamr/dlac005
  3. Sinclair MR, Souli M, Ruffin F, Park LP, Dagher M, Eichenberger EM, Maskarinec SA, Thaden JT, Mohnasky M, Wyatt CM, Fowler VG, Jr. Staphylococcus aureus Bacteremia Among Patients Receiving Maintenance Hemodialysis: Trends in Clinical Characteristics and Outcomes. Am J Kidney Dis. 2022;79(3):393-403.e391. doi10.1053/j.ajkd.2021.06.018
  4. Dannhauer M, Huang Z, Beynel L, Wood E, Bukhari-Parlakturk N, Peterchev AV. TAP: targeting and analysis pipeline for optimization and verification of coil placement in transcranial magnetic stimulation. J Neural Eng. 2022;19(2). doi10.1088/1741-2552/ac63a4
  5. Clowse MEB, Eudy AM, Balevic S, Sanders-Schmidler G, Kosinski A, Fischer-Betz R, Gladman DD, Molad Y, Nalli C, Mokbel A, Tincani A, Urowitz M, Bay C, van Noord M, Petri M. Hydroxychloroquine in the pregnancies of women with lupus: a meta-analysis of individual participant data. Lupus Sci Med. 2022;9(1). doi10.1136/lupus-2021-000651
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  7. Fish LJ, Harrison SE, McDonald JA, Yelverton V, Williams C, Walter EB, Vasudevan L. Key stakeholder perspectives on challenges and opportunities for rural HPV vaccination in North and South Carolina. Human Vaccines Immunother. 2022;1-8. doi10.1080/21645515.2022.2058264
  1. Wheeler SM, Myers SO, Swamy GK, Myers ER. Estimated Prevalence of Risk Factors for Preeclampsia Among Individuals Giving Birth in the US in 2019. JAMA Netw Open. 2022;5(1):e2142343. doi10.1001/jamanetworkopen.2021.42343
  2. Reid HW, Broadwater G, Montes de Oca MK, Selvan B, Fayanju O, Havrilesky LJ, Davidson BA. Distress screening in endometrial cancer leads to disparity in referral to support services. Gynecol Oncol. 2022;164(3):622-627. doi10.1016/j.ygyno.2022.01.001
  3. Kobe EA, Lewinski AA, Jeffreys AS, Smith VA, Coffman CJ, Danus SM, Sidoli E, Greck BD, Horne L, Saxon DR, Shook S, Aguirre LE, Esquibel MG, Evenson C, Elizagaray C, Nelson V, Zeek A, Weppner WG, Scodellaro S, Perdew CJ, Jackson GL, Steinhauser K, Bosworth HB, Edelman D, Crowley MJ. Implementation of an Intensive Telehealth Intervention for Rural Patients with Clinic-Refractory Diabetes. J Gen Intern Med. 2022:1-9. doi10.1007/s11606-021-07281-8
  4. Halpern SE, Kesseli SJ, Au S, Krischak MK, Olaso DG, Smith H, Tipton G, Jamieson IR, Barbas AS, Haney JC, Klapper JA, Hartwig MG. Lung transplantation after ex vivo lung perfusion versus static cold storage: An institutional cost analysis. Am J Transplant. 2022;22(2):552-564. doi10.1111/ajt.16794
  5. Denoble A, Reid HW, Krischak M, Rosett H, Sachdeva S, Weaver K, Heine PR, Dotters-Katz S. Bad bugs: antibiotic-resistant bacteriuria in pregnancy and risk of pyelonephritis. Am J Obstet Gynecol MFM. 2022;4(2):100540. doi10.1016/j.ajogmf.2021.100540
  6. Darling AJ, Federspiel JJ, Wein LE, Swamy GK, Dotters-Katz SK. Morbidity of late-season influenza during pregnancy. Am J Obstet Gynecol MFM. 2022;4(1):100487. doi10.1016/j.ajogmf.2021.100487
  7. Abar B, Kwon N, Allen NB, Lau T, Johnson LG, Gall K, Adams SB. Outcomes of Surgical Reconstruction Using Custom 3D-Printed Porous Titanium Implants for Critical-Sized Bone Defects of the Foot and Ankle. Foot and Ankle International. 2022. doi10.1177/10711007221077113


  1. Zheng K, Lawton R, Zheng DZ, Huang E. Neural Networks in Examining the Association of Built Environment with Diabetes Prevalence. Diabetes. 2021;70:3. doi10.2337/db21-329-OR
  2. Yang X, Sun J, Patel RC, Zhang J, Guo S, Zheng Q, Olex AL, Olatosi B, Weissman SB, Islam JY, Chute CG, Haendel M, Kirk GD, Li X. Associations between HIV infection and clinical spectrum of COVID-19: a population level analysis based on US National COVID Cohort Collaborative (N3C) data. Lancet HIV. 2021;8(11):e690-e700. doi10.1016/s2352-3018(21)00239-3
  3. Xu H, Lee HJ, Schmitz R, Shaw BI, Li S, Kirk AD. Age-related effects on thymic output and homeostatic T cell expansion following depletional induction in renal transplant recipients. Am J Transplant. 2021;21(9):3163-3174. doi10.1111/ajt.16625
  4. Williamson T, Hodges S, Yang LZ, Lee HJ, Gabr M, Ugiliweneza B, Boakye M, Shaffrey CI, Goodwin CR, Karikari IO, Lad S, Abd-El-Barr M. Impact of US hospital center and interhospital transfer on spinal cord injury management: An analysis of the National Trauma Data Bank. J Trauma Acute Care Surg. 2021;90(6):1067-1076. doi10.1097/ta.0000000000003165
  5. Welsh LK, Davalos G, Diaz R, Narvaez A, Perez JE, Castro M, Kuchibhatla M, Risoli T, Portenier D, Guerron AD. Magnetic Liver Retraction Decreases Postoperative Pain and Length of Stay in Bariatric Surgery Compared to Nathanson Device. J Laparoendosc Adv Surg Tech. 2021;31(2):194-202. doi10.1089/lap.2020.0388
  6. Watson CH, Puechl AM, Lim S, Monuszko K, Truong T, Havrilesky LJ, Davidson BA. Chemotherapy discontinuation processes in a gynecologic oncology population. Gynecol Oncol. 2021;161(2):508-511. doi10.1016/j.ygyno.2021.03.003
  7. Turner EL, Platt AC, Gallis JA, Tetreault K, Easter C, McKenzie JE, Nash S, Forbes AB, Hemming K, Adrion C, Akooji N, Bhangu A, Bridgwood B, Budgell E, Chan CL, Campbell M, Collinson M, Copas A, Eldridge S, Forster AS, Girling A, Glasbey J, Goulao B, Hackett S, Hamborg T, Hooper R, James K, Jarvis CI, Jones B, Kahan BC, Kanaan M, Kendall L, Kristunas C, Leyrat C, Macneill SJ, Madurasinghe VW, Martin J, Mwandigha LM, Nepogodiev D, Omar O, Pankhurst LA, Perry H, Rombach I, Stuart B, Thompson JA, Wagner AP, Wilson N, Caille A, Yepnang AMM, Tavernier E, Giraudeau B, Diakou LAN, Taljaard M, Dixon SN, Moerbeek M, Grantham KL, Kasza J, Cao S, Harding M, Kusibab K, Lee HJ, McCormack K, Moran K, Parish A, Simmons R, Truong T, Vissoci JR, Wang T, Wang X, Weber J, Wilson J, Yang S, Yang Z, Bishop J, Cheed V, Gill A, Handley K, Hardy P, Hewitt CA, Ives N, Mehta S, Patel S, Sun Y, Woolley R. Completeness of reporting and risks of overstating impact in cluster randomised trials: a systematic review. Lancet Glob Health. 2021;9(8):E1163-E1168. <Go to ISI>://WOS:000677505700033.
  8. Tsai SL, Sun M, Asbury ML, Weber JM, Truong T, Deans E. Novel Spaced Repetition Flashcard System for the In-training Examination for Obstetrics and Gynecology. Med Sci Educ. 2021;31(4):1393-1399. doi10.1007/s40670-021-01320-z
  9. Trumpis M, Chiang CH, Orsborn AL, Bent B, Li J, Rogers JA, Pesaran B, Cogan G, Viventi J. Sufficient sampling for kriging prediction of cortical potential in rat, monkey, and human µECoG. J Neural Eng. 2021;18(3). doi10.1088/1741-2552/abd460
  10. Toffaletti JG, Buckner KA, Liu B, Green CL. Retrospective Analysis of Quality Control Data Using Pooled Blood to Compare Agreement within Two Models of Blood Gas Analyzers. J Appl Lab Med. 2021;6(5):1228-1236. doi10.1093/jalm/jfab029
  11. Thomas JA, Foraker RE, Zamstein N, Payne PRO, Wilcox AB. Demonstrating an approach for evaluating synthetic geospatial and temporal epidemiologic data utility: Results from analyzing >1.8 million SARS-CoV-2 tests in the United States National COVID Cohort Collaborative (N3C). medRxiv. 2021. doi10.1101/2021.07.06.21259051
  13. Swartz JJ, Rowe C, Truong T, Bryant AG, Morse JE, Stuart GS. Comparing Website Identification for Crisis Pregnancy Centers and Abortion Clinics. Womens Health Issues. 2021;31(5):432-439. doi10.1016/j.whi.2021.06.001
  14. Stephens B, Cummings JN. Knowledge creation through collaboration: The role of shared institutional affiliations and physical proximity. J Assoc Inf Sci Technol. 2021;72(11):1337-1353. doi10.1002/asi.24491
  15. Steinberger AE, Youngwirth LM, Kim SE, Duke NN, Skinner A, Gordee A, Kuchibhatla M, Armstrong S, Seymour KA. Adolescent Bariatric Surgery: Racial Disparities in 30-Day Outcomes Using the MBSAQIP from 2015 to 2018. Obes Surg. 2021;31(8):3776-3785. doi10.1007/s11695-021-05500-z
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  1. Seely KR, Wang KL, Tai V, Prakalapakorn SG, Chiu SJ, Viehland C, Grace S, Izatt JA, Freedman SF, Toth CA. Auto-Processed Retinal Vessel Shadow View Images From Bedside Optical Coherence Tomography to Evaluate Plus Disease in Retinopathy of Prematurity. Transl Vis Sci Technol. 2020;9(9):16. doi10.1167/tvst.9.9.16
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  1. Whitson H. Aging Eyes in Aging Bodies: What Does a Graying Population Mean for the Vision Care and Research Community? Invest Ophthalmol Vis Sci. 2019;60(9):2. <Go to ISI>://WOS:000488628106359.
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  1. Williams ZF, Olivere LA, Schroder J, Cox MW, Long CA, Southerland KW. Simultaneous transcarotid artery revascularization with flow reversal and coronary artery bypass grafting: A novel hybrid technique. J Vasc Surg Cases Innov Tech. 2019;5(4):572-575. doi10.1016/j.jvscit.2019.08.010
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  1. Zambeli-Ljepović A, Wang F, Dinan MA, Hyslop T, Roman SA, Sosa JA, Scheri RP. Low-Risk Thyroid Cancer in Elderly: Total Thyroidectomy/RAI Predominates but Lacks Survival Advantage. J Surg Res. 2019;243:189-197. doi10.1016/j.jss.2019.05.029
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