Duke/RTI Collaborative Translational Research Grants

Applications for this funding program are currently closed.

This pilot program is designed to facilitate novel clinical and translational research that applies or accelerates discovery into testing in clinical or population settings. Projects will advance solutions by applying discoveries generated during research in the laboratory, and in preclinical studies in the areas of medicinal chemistry, computational chemistry, High Throughput Screening (HTS) and assay development, in vitro absorption–distribution–metabolism–excretion–toxicity (ADMET) and pharmacology and in vivo pharmacokinetics in clinical or population settings.

The Duke Clinical and Translational Science Institute (Duke CTSI) is the academic home of the National Institutes of Health’s Clinical and Translational Science Awards (CTSA) pilot funding programs at Duke University, is partnering with RTI International (RTI) to support new inter-institutional collaborative research teams. 

Duke CTSI and RTI are interested in the following types of translational research projects that foster collaboration between the two institutions:

  • Research that generates translational discoveries relevant to human health or disease, regardless of whether the context of the discovery is the laboratory, in animal models or the field.

  • Research that applies or accelerates discovery into testing in clinical or population settings.

Key Dates

  • Optional Letter of Intent (LOI): July 14, 2021

  • Invited LOI Presentation/Consultation: July 19-23 2021

  • Invited Application Submission Deadline: August 17, 2021

  • Selection of Awardees: September 2021

  • Funding Period: The budget period is for 12 months beginning October 1, 2021 – September 30, 2022

Eligibility Requirements

  • Proposed projects must involve a lead investigator from Duke (full-faculty appointment) and a lead investigator from RTI. Proposals are encouraged from teams of investigators from different disciplines.

  • If needed and requested prior to the Optional LOI submission, assistance can be provided to help identify an RTI investigator by contacting Tarun Saxena at tarun.saxena@duke.edu by July 07, 2021.

  • More than one proposal may be submitted by a Duke Faculty member acting as PI, but the Duke Faculty member is only eligible to receive one award as PI from this funding mechanism during a given funding Duke RTI Pilots RFA 2021 Cycle 2 cycle.


The research activities at each participating institution will be funded by the Duke CTSI and RTI.  The Duke CTSI and RTI will fund up to $50,000 per award ($25,000 per institution).

Note for Duke Investigators: This award is internally funded and does not need to be routed through ORA.

Proposal Preparation

The CTSI and RTI strongly recommend involving a biostatistician in the invited full application development process. The online application form will ask for the name of the biostatistician who consulted on the proposal. Investigators without access to a biostatistician can request support through the Duke CTSI Biostatistics Core by submitting a Core Resource Request form.

consult with CTSI is recommended.

Letter of Intent and Application Procedure

The Letter of Intent (LOI) will be submitted via Duke’s MyResearchProposal online submission system.​

View the RFA for full application instructions


For additional information on this funding opportunity, please contact Tarun Saxena at CTSIfunding@duke.edu. To schedule