Completed Studies

A Duke University study tested how well a new online, interactive educational program worked, compared to diabetes education on a traditional website. We studied a program called Learning In Virtual Environments or LIVE — a social network on the Internet like a video game that allows people to talk with each other through avatars, or cartoon representations of themselves. 

This study was funded by the National Institutes of Health and enrolled 150 participants at Duke sites.

Principal Investigator: Wei Pan, PhD

The Duke APOL1 Research Biorepository study supports new discoveries in kidney disease to better understand why people of African descent are at higher risk.

Principal Investigator: Dr. Opeyemi Olabisi




The MURDOCK Cabarrus County COVID-19 Prevalence and Immunity (C3PI) Study was launched to understand COVID-19 prevalence and immunity in the community and to monitor the disease over time.

The Study started in June 2020, enrollment reached 1,426 participants, and study activities concluded in November 2021.

The N.C. Department of Health and Human Services also collaborated with the University of North Carolina at Chapel Hill and East Carolina University on similar research in Chatham and Pitt counties.

Principal Investigator: Dr. L. Kristin Newby

Co-Principal Investigator: Dr. Chris Woods

Duke TransPop managed the MURDOCK COVID-19 Opinions, Perceptions & Experiences (COPE) Study, a collaboration of the Duke Clinical and Translational Science Institute (CTSI) and the Duke Social Sciences Research Institute (SSRI).

The MURDOCK COPE Study is a nested cohort of the MURDOCK Study. It looked at how participants feel in response to the COVID-19 pandemic and related events, how the pandemic and associated regulations affected them and their family, and how these perceptions and experiences changed over time.

Principal Investigator: Dr. Alexandra Cooper

Co-Principal Investigator: Dr. L. Kristin Newby

This Prostate Cancer study analyzed existing samples from more than 600 MURDOCK Study participants in hopes of better understanding why African American men more frequently have a more aggressive form of prostate cancer. Researchers wanted to learn more about prostate cancer at the molecular level. 

 This study represents collaboration between DTRI’s Population Health Research group, the MURDOCK Study and the Duke Cancer Institute’s GU Oncology, Cancer Control and Population Sciences and Biostatistics Programs.

Principal Investigator: Steven R. Patierno, PhD

Lead Sub Investigator: Jennifer A. Freedman, PhD

This study sought to improve our understanding of the genetic markers associated with severe acne and the adverse response to oral isotretinoin (Accutane) treatment, leading to the development of safer and more effective treatments.

The study enrolled 122 participants who were diagnosed with severe acne vulgarism and had received oral isotretinoin treatment (eg. Accutane, Amnesteem, Claravis, Sotret). 

Principal Investigator: Dr. Russell Hall (interim)

This study researched whether text messaging is an effective way to help people who want to quit using smokeless tobacco. Examples of smokeless tobacco include chewing tobacco, dip, and snuff.

Principal InvestigatorDr. Devon Noonan


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This study was an initiative to bring together data that facilitated research using social determinants of health to examine and understand health disparities.

Paul Bendich, PhD

The goal of the study was to find out what people think about researchers using medical records for health-related studies.

Principal Investigator: Laura M. Beskow, MPH, PhD

The Mid Southern NIDA Node is a primary care practice-based research network that offers access to patient populations and clinicians who are interested in engaging in research projects and using Electronic Health Records (EHR) for research. 

Principal Investigator: Li-Tzy Wu< PhD

The purpose of the research was to determine whether a common genetic variation in men causes abnormal sperm function and whether treatment with a dietary supplement (betaine) can correct this problem.

Principal Investigator: Steven H. Zeisel, MD, PhD