Center for Precision Health Welcomes New Faculty Leaders

The Center for Precision Health (CPH) has announced the addition of 10 faculty members. CPH is a collaborative effort between Duke CTSI and the Precision Genomics Collaboratory (PGC) that works to harness the power of genomic, biomarker, and health data to transform patient care and population health. 

These faculty members will help CPH expand clinical genetics, conduct clinically relevant translational research, perform cutting-edge implementation science, engage with and build trust in the community, and educate the workforce of tomorrow.

“We are thrilled to have an amazing cohort of faculty joining the Center for Precision Health,” said CPH Director Svati H. Shah, MD, MHS, the Ursula Geller Distinguished Professor of Research in Cardiovascular Diseases and associate dean for translational research. “Their talents and expertise will help us expand our basic, translational, and clinical research and allow us to harness the power of genomic, biomarker and health data to transform patient care and population health.”

Leadership Team 

Eun-Sil Shelley Hwang, MD, MPH
Mary and Deryl Hart Distinguished Professor of Surgery, Oncology
Vice Chair of Research in the Department of Surgery
Professor of Radiology
Member of the Duke Cancer Institute

A world-renowned surgeon-scientist and leader in the field of breast surgical oncology, Hwang currently is focused on formulating a translational framework in which to test the efficacy of non-surgical interventions for ductal carcinoma in situ of the breast. She is leading a global reassessment of what defines breast cancer and is revolutionizing the approach to this disease, highlighting non-surgical approaches.

Mihai V. Podgoreanu, MD
Associate Professor of Anesthesiology
Chief, Division of Cardiac Anesthesiology

Podgoreanu’s research includes using functional genomics with perioperative myocardial injury and vein graft disease, and clinico-genomic risk prediction models for perioperative and long-term adverse cardiovascular outcomes following heart surgery.

Senthil Selvaraj, MD, MS, MA
Assistant Professor of Medicine, Section of Advanced Heart Failure and Transplant, Division of Cardiology
Member of Duke Molecular Physiology Institute

Selvaraj’s translational research explores the therapeutic relevance of cardiovascular metabolism to patients with heart failure. Through early phase work, his research employs deep phenotyping to decipher metabolic mechanisms that may be leveraged for cardiovascular benefit. In particular, his research seeks to understand the implications of changing fuel substrates for the heart and other organs.

Deepak Voora, MD
Associate Professor of Medicine, Cardiology
Executive Director, VA National Pharmacogenomics Program

Voora is interested in systems and translational pharmacogenetics, and his work spans the spectrum of discovering novel genomic biomarkers that describe drug responses to implementing genomic tools that health care providers can use to tailor drug therapy in clinical practice.

Faculty Members

Susanne Haga, PhD
Professor in Medicine, General Internal Medicine
Associate Research Professor in the Sanford School of Public Policy
Associate Research Professor of Biology
Affiliate of the Duke Initiative for Science & Society

Haga’s research interests focus on issues affecting the translation of genomics to clinical practice with an interest in professional, public, and patient education. She develops educational materials about genomic research in general, pharmacogenetic testing, and communicating genetic test results, in addition to undergraduate teaching in genetics/genomics, ethics, and policy.

Micah McClain, MD, PhD
Associate Professor of Medicine, Infectious Diseases

McClain is an infectious disease specialist who studies host immunologic and genomic responses to infection in order to develop transcriptional and proteomic biomarker assays for diagnosis and severity prediction in a spectrum of bacterial, viral, and fungal infections both in the US and abroad.

Lori Orlando, MD, MHS
Professor of Medicine, General Internal Medicine

Orlando’s research interests are in implementation research as it applies to genomic medicine and in particular leveraging informatics technologies to enhance risk stratification for targeting preventive health services. She has led the development of MeTree, patient-facing family health history based risk assessment and clinical decision support program designed to facilitate the uptake of risk stratified evidence-based guidelines.

Nina Sperber, PhD
Associate Professor in Population Health Sciences
Core Faculty Member, Duke-Margolis Center for Health Policy

Sperber’s research focuses on understanding how to improve delivery of new evidence-based services within health care systems using study designs that integrate qualitative and quantitative methods. Her work is based in implementing innovation for precision medicine. She uses Implementation Science and Systems Thinking approaches.

An-Kwok Ian Wong, MD
Assistant Professor of Medicine, Pulmonary, Allergy, and Critical Care Medicine
Assistant Professor in Biostatistics & Bioinformatics

Wong leverages medical informatics, data science, and machine learning on electronic health record data to discover new insights and develop artificial intelligence and machine learning-based clinical decision support systems.

Christopher W. Woods, MD, MPH
Wolfgang Joklik Distinguished Professor of Global Health, Medicine, Infectious Disease
Professor of Medicine, Infectious Disease
Research Professor of Global Health
Professor in Pathology
Member of the Duke Human Vaccine Institute

Woods is interested in developing medical microbiology capacity in the developing world and the epidemiology of emerging and re-emerging infectious diseases. His research focuses on developing novel diagnostic approaches to infectious disease and the potential for interspecies transmission of pathogens.