Publications Detail Research from Project Baseline Health Study

Two journals have published findings from the Project Baseline Health Study, a community-based research initiative by Duke University School of Medicine, Stanford Medicine, Verily Life Sciences, and others that collected, organized, and analyzed broad health data from thousands of participants over more than four years. 

In the Journal of Cardiac Failure, researchers detail how real-world walking behaviors are associated with early-stage heart failure. Using data collected by an investigational device worn by study participants, researchers found that digital measures of walking captured by sensors could complement clinic-based testing to identify and monitor pre-symptomatic heart failure. 

In Scientific Reports, researchers identify characteristics and clinical conditions associated with hand grip strength, a reliably measured biomarker that is a strong predictor of incident cardiovascular disease. Using the study's detailed demographic, occupational, social, lifestyle, and clinical data, they found several new variables associated with hand grip strength and others that corroborate previous research.

Duke CTSI enrolled more than 1,000 Project Baseline Health Study participants in two locations — Durham and Duke Kannapolis, the clinical research site on the North Carolina Research Campus. Duke Kannapolis is part of the Center for Precision Health within CTSI.

Read the wearable device and hand grip strength papers.