The Duke CTSI is supported in part by the Duke Clinical and Translational Science Award, NIH Award UL1TR002553. The CTSA initiative is led by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health. The CTSA designates several core capabilities for grant-holding institutions to address. Programs and teams who support these capabilities at Duke, and key contacts for each, are included below.
Provides oversight, leadership, integration, coordination, and dissemination of all Duke CTSA programs and activities. Acts as a central collaborative platform to catalyze discoveries across Duke’s academic health center and entire University campus. More about the Administrative Core.
Susanna Naggie, MD, MHS
Department of Medicine
Director, Duke CTSI
Jennifer Li, MD
Department of Pediatrics
Co-Principal Investigator, Duke CTSA
Jim McNamara, MD
Department of Neurobiology
Co-Principal Investigator, Duke CTSA
Cinthia Sanchez, PhD
Program Director, Duke CTSA
Director of Strategic Communications, Duke CTSI
Grants and Contracts Manager, Duke CTSI
Housed in the Department of Biostatistics and Bioinformatics (B&B) and the CTSI, BERD helps investigators identify quantitative/qualitative collaborators. As appropriate, they connect investigators with quantitative and qualitative partners across Duke and partner institutions. When there are not sufficient collaboration resources available, BERD builds and house teams of collaborative methodologists who work on long term collaborations with clinical and translational investigators.
Grounded in a health equity perspective, CERI seeks to improve relevance and uptake of scientific discoveries through stakeholder engagement. Programs and services promote community-engaged research through cultivating meaningful and equitable research-community stakeholder partnerships, enhancing capacity to conduct stakeholder-engaged research, and fostering trust and transparency in research via improved knowledge, information sharing, and power sharing.
Connects trainees, shares resources, and increases efficiencies to enhance the career development of Duke research scholars. Programmatic goals include: (1) Connecting scholars with resources opportunities, and each other; (2) Creating synergy by strengthening connections among career development programs; (3) Sharing best practices and resources for program diversity among scholars, mentors, and programs.
Supports the development of novel methods and proof-of-concept evaluation of therapeutic agents, biomedical devices, diagnostic tests, and technologies. The goal is to transform translational research by promoting basic and clinical investigator collaboration, offering funding, providing project management support and technical knowledge, and facilitating access to resources and expertise within and outside Duke University.
Provides a basis for data science discovery and engineering of translational biomedical informatics applications. Aims are to form and fund teams to address new health data science questions through an incubator program; develop new data science methods and informatics applications and implement and disseminate data science tools.
Provides infrastructure support for research teams and CTSA Cores to promote equity, anti-bias, and anti-racism across all aspects of the research process and environment. Services include curriculum development and training, consultations to support the development of intentional and strategic diversity recruitment plans, and resources and tools to promote an anti-racist and anti-bias research environment.
As part of the CTSA Administration core, ESP applies principles of continuous quality improvement and evidence-based decision-making throughout and across CTSA functions. ESP aims to advance CTSA opportunities for organizational learning and understanding of impact. The primary focus is on the Duke hub but ESP also contributes to CTSA nationally, including participation in the CLIC-CTSA Program Evaluators Group.
Focuses on innovative approaches that accelerate and transform scientific discoveries through data and applications that fuel translational research, data science and precision health; expand capacity for conducting collaborative network research and sharing network best practices; and provide access to opportunities for informatics training and professional development.
(1) Provides junior faculty scholars with fundamental transdisciplinary research skills required for successful translational research careers; (2) Prepares junior faculty scholars to successfully employ fundamental team science approaches to enable innovation and impact; (3) Promotes a highly diverse translational research workforce.
Run by the Duke Office of Clinical Research (DOCR), ensures rigorous and efficient conduct of clinical research while partnering with and protecting research participants. DOCR supports Clinical Research Units and Oversight Organizations with tools and training, and houses multiple research support services, including the Duke Early Phase Research Unit (DEPRU) and Duke Research at Pickett (R@P).
Catee Mullen, MS
Director, Research Operations, DOCR
Hub of our participation in several research networks and our recruitment innovation team, supporting Duke Research by ensuring our robust involvement in the Trial Innovation Network (TIN), Accrual to Clinical Trials (ACT), and PCORnet as well as providing operational oversight for the Primary Care Research Consortium (PCRC). RIC provides guidance, tools, and training in effective outreach, engagement, recruitment, and retention to Duke research.
Assists clinical and translational researchers meet U.S. Food and Drug Administration (FDA) regulatory requirements. The Core provides full-spectrum regulatory and quality assurance support, including strategic development; preclinical testing and Good Manufacturing Practice (GMP) guidance; regulatory submissions and meetings with the FDA; and regulatory education and training.
Facilitates research that promotes health equity for groups that have traditionally been under-represented in health research or excluded altogether.
Enables equitable and effective boundary-spanning teams across Duke University, Duke Health, and our institutional collaborators by: (1) advancing our understanding of what factors contribute to effective team science by conducting research studies to advance the Science of Team Science; (2) promoting team science skills and concepts across the institution; and (3) developing intentional career paths for post-award support of team science.
Duke CTSI, Duke Office of Research Initiatives
Comprises 3 programs: a two-year master’s program in clinical research for medical students, a postdoctoral program supporting research training for outstanding junior scientists, and a pre-doctoral scholarship program offering clinical and translational research experience and training for predoctoral students in medicine.
An innovative collaboration addressing critical roadblocks in clinical research and accelerating the translation of novel interventions into life-saving therapies.
Catee Mullen, MS
Director, Research Operations, Duke Office of Clinical Research
Ensures that our research workforce has the skills and knowledge necessary to advance translation of discoveries into improved health outcomes. The Core offers an evolving portfolio of training opportunities to enhance and diversify the workforce, addressing a range of learners—from students to staff to faculty.
Co-Director, Workforce Development