Duke participates in several Clinical Data Research Networks (CDRNs) that make it easier than ever to conduct multi-site studies by enabling access to well-curated EHR data at all member institutions, including Duke.

Leveraging the CDRN program provides many benefits to your research:

  • Quickly get counts of patients meeting your eligibility criteria

  • Assess feasibility of multi-site studies and engage in data-driven site selection

  • Find collaborators at other member institutions

  • Navigate the associated regulatory processes

Our team can help you learn about the Duke CDRN program and the process for accessing CDRN resources. 

Contact us to get started with clinical data.

CDRNs available to Duke investigators

STAR Clinical Research Network (formerly Mid-South CDRN) — A PCORnet Member Network

  • Scope: Local, Regional, and National

  • Population: 68+ million (PCORnet); 14+ million (STAR)

  • Who is Involved: Duke University Health System; Mayo Clinic; Vanderbilt University Medical Center; Meharry Medical College; UNC-Chapel Hill; Wake Forest Baptist Health

Through our participation in this network, we have access to PCORnet member networks and a broad array of clinical data, informatics tools, patients, providers, collaborators, and systems that enable you to address research questions. The objective of STAR includes robustly supporting comparative effectiveness studies, pragmatic clinical trials, health system innovation, and the other research needs of our stakeholders and partners.

  ACT Network at Duke (i2b2)

  • Scope: Local and National

  • Population: ~100 M

  • Who Is Involved: 39 CTSA institutions (18 more currently staging)

The ACT Network is a real-time platform allowing researchers to explore and validate feasibility for clinical studies from the comfort of their desktop.

Use ACT to discover patient cohorts at Duke and more than 39 sites across the nation. Duke CTSI has made the ACT Network available to all Duke researchers at no cost, but you must request access to receive credentials in the ACT portal.

Once registration is complete and you have received your credentials, you can use i2b2 to query Duke EHR-data and SHRINE to query Duke data and data from the entire network for aggregate counts.

ACT was developed collaboratively by members of NCATS’ Clinical and Translational Science Award (CTSA) Consortium, with funding from the NIH National Center for Advancing Translational Sciences.

Have questions about ACT? e-Mail CTSI_ACT@dm.duke.edu.

Clinical Data Research Networks News